Publications

The Research behind NeuroCatch

Since the earliest evoked responses were reported in 1939, there are now over 160,000 published studies on the PubMed.gov database. The NeuroCatch Platform measures three event-related potentials (ERPs) that are direct measures of cognitive function: N100, P300, and N400 responses, for which over 103,600 studies have been published.

Reference Literature

Neill MG, Fletcher EKS, Larson E, Fraser K, Ramsay S, Smirl JD, and Emery CA (2025). Neurophysiology of Downhill Mountain Bike Athletes—Benchmark Assessments of Event-Related Potentials. Sensors (Basel, Switzerland). 25(17):5388. https://doi.org/10.3390/s25175388

Moser N, Popovic MR, Kalsi-Ryan S (2024). Effectiveness of personalized rehabilitation in adults suffering from persistent concussion symptoms as compared to usual care: a randomized control trial protocol. BMC Neurology. 24:239. https://doi.org/10.1186/s12883-024-03700-5

Macoun SJ, Silverman JM, Brunet PR, Lewis JM, Kafoteka E, Ziba T, Kirby ED, Ighalo J, D’Arcy RCN, and O’Brien N (2025).
A Pilot Feasibility Study of a Home Tablet-Based Neurorehabilitation Program with Objective Brain Vital Signs Assessment in Child Survivors of Cerebral Malaria.
The American Journal of Tropical Medicine and Hygiene. https://doi.org/10.4269/ajtmh.25-0492

Medvedev G, Kirby ED, Harding K, Glashutter M, Frizzell TO, Song X, and D’Arcy RCN (2025). Initial Comparison of Routine Electroencephalography and Event-Related Potentials in Patients with Cognitive Complaints. Canadian Journal of Neurological Sciences. 47(1): 37–43. https://doi.org/10.1017/cjn.2019.290

Kirby, ED, Jones K, Campbell N, Fickling SD, and D’Arcy RCN (2025). Objective Neurophysiological Measures of Cognitive Performance in Elite Ice Hockey Players. Open Access Journal of Sports Medicine. 16 (January):15–24. https://doi.org/10.2147/OAJSM.S494589.

Kirby ED, Beyst B, Beyst J, Brodie SM and D’Arcy RCN (2024). A retrospective, observational study of real-world clinical data from the Cognitive Function Development Therapy program. Front. Hum. Neurosci. 18:1508815. doi: 10.3389/fnhum.2024.1508815

D’Arcy, R. C. N., McCarthy, D., Harrison, D., Levenberg, Z., Wan, J., Hepburn, A., Kirby, E. D., Yardley, T., Yamada-Bagg, N., Fickling, S. D., Munce, T. A., Dodick, D. W., Ahmad, C., & Stein, K. S. (2024). An objective neurophysiological study of subconcussion in female and male high school student athletes. Scientific reports, 14(1), 28929. https://doi.org/10.1038/s41598-024-80262-z

Munce, T.A., Fickling, S.D., Nijjer, S., Poel, D.N., & D’Arcy, R.C.N. (2024). Mixed martial art athletes demonstrate different brain vital sign profiles compared to matched controls at baseline. Frontiers in Neurology, 15. https://doi.org/10.3389/fneur.2024.1438368

Ighalo J, Kirby ED, Song X, Fickling SD, Pawlowski G, Ghosh Hajra S, Liu CC, Menon C, Shah SA, Knoefel F, D’Arcy RCN (2024). Brain vital signs as a quantitative measure of cognition: Methodological implementation in a care home environment. Heliyon. DOI: https://doi.org/10.1016/j.heliyon.2024.e28982

Jones KB, Frizzell T, Fickling SD, Pawlowski G, Brodie SM, Lakhani B, Venter J, D’Arcy RCN (2024). Brain vital sign monitoring of sleep deprivation detects situational cognitive impairment. Frontiers in Human Neuroscience. DOI: https://doi.org/10.3389/fnhum.2024.1358551

D’Arcy, R.C.N., Campbell, N. (2023). Clinical Use Case of the NeuroCatch® Platform: Treating Concussion and Unlocking Peak Brain Performance. NeuroCatch Inc.

Kirby ED, Jones CB, Fickling SD, Pawlowski G, Brodie SM, Boyd LA, Venter J, Moser N, Kalsi-Ryan S, Medvedev G and D’Arcy RCN. (2023) Real world evidence of improved attention and cognition during physical therapy paired with neuromodulation: a brain vital signs study. Frontiers in Human Neuroscience. 17:1209480. doi: 10.3389/fnhum.2023.1209480

D’Arcy, R.C.N., Campbell, N., Fickling S. (2022). A Practical and Accessible Measure of Brain Vital Signs: the NeuroCatch® Platform. NeuroCatch Inc.

Nayoung Kim, William D. Watson, Eric Caliendo, Sophie Nowak, Nicholas D. Schiff, Sudhin A. Shah, N. Jeremy Hill. (Sep 2022). Objective neurophysiological markers of cognition after pediatric brain injury. Neurology Clinical Practice. DOI: 10.1212/CPJ.0000000000200066. (Independent Study)

Fickling, S.D., Poel, D.N., Dorman, J.C., D’Arcy, R.C.N., & Munce, T.A. (2021). Subconcussive changes in youth football players: Objective evidence using brain vital signs and instrumented accelerometers. Brain Communications, fcab286.

Hajra, S. G., Liu, C. C., Fickling, S. D., Pawlowski, G. M., Song, X., & D’Arcy, R. (2021). Event Related Potential Signal Capture Can Be Enhanced through Dynamic SNR-Weighted Channel Pooling. Sensors (Basel, Switzerland), 21(21), 7258.

D’Arcy, R., Sandhu, J. K., Marshall, S., & Besemann, M. (2021). Mitigating Long-Term COVID-19 Consequences on Brain Health. Frontiers in neurology, 12, 630986.

Carrick, F. R., Pagnacco, G., Azzolino, S. F., Hunfalvay, M., Oggero, E., Frizzell, T., Smith, C. J., Pawlowski, G., Campbell, N., Fickling, S. D., Lakhani, B., & D’Arcy, R. (2021). Brain Vital Signs in Elite Ice Hockey: Towards Characterizing Objective and Specific Neurophysiological Reference Values for Concussion Management. Frontiers in neuroscience, 15, 670563. https://doi.org/10.3389/fnins.2021.670563

Fickling, S. D., Smith, A. M., Stuart, M. J., Dodick, D. W., Farrell, K., Pender, S. C., & D’Arcy, R. C. (2021). Subconcussive brain vital signs changes predict head-impact exposure in ice hockey players. Brain Communications, 3(2), fcab019. doi:10.1093/braincomms/fcab019

Ghosh Hajra, S., Gopinath, S., Liu, C.L., Pawlowski, G., Fickling, S.D., Song, X., & D’Arcy, R.C.N. (2020). Enabling event related potential assessments using low-density electrode arrays: A new technique for denoising individual channel EEG data. IEEE Xplore Digital Library, In Press.

Fickling, S.D., Greene, T., Greene, D., Frehlick, Z., Campbell, N., Etheridge, T., Smith, C., Bollinger, F., Danilov, Y., Rizzotti, R., Livingstone, A., Lakhani, B., & D’Arcy, R.C.N. (2020). Brain vital signs detect cognitive improvements during combined physical therapy and neuromodulation in rehabilitation from severe traumatic brain injury: Case report. Frontiers in Human Neuroscience. 14, 347. doi: 10.3389/fnhum.2020.00347

Smith, C., Lakhani, B., Livingstone, A., Fickling, S., Campbell, N., Tannouri, P., Danilov, Y., Sackier, J., & D’Arcy, R.C.N. (2020). Brain vital signs detect information processing differences when neuromodulation is used during cognitive skills training. Frontiers in Human Neuroscience. 14, 358. doi: 10.3389/fnhum.2020.00358

Fickling, S.D., Liu, C.C., Ghosh Hajra, S., Song, X., & D’Arcy, R.C.N. (2019). Good data? The EEG quality index for automated assessment of signal quality. IEEE XPlore. 2019, 0219-0229. doi: 10.1109/IEMCON.2019.8936246

Fickling, S.D., Bolinger, F., Pawlowski, G., Ghosh Hajra, S., Liu, C.C., Song, X., & D’Arcy, R.C.N. (2020). Distant Sensor Prediction of Event-Related Potentials. IEEE Transactions on Biomedical Engineering. 67(10), 2916 – 2924. doi: 10.1109/TBME.2020.2973617

Smith, A.N., Alford, P.A., Aubry, M., Benson, B., Black, A., Brooks, A., Burke, C., D’Arcy, R.C.N., Dodick, D., Eaves, M., Eickhoff, C., Erredge, K., Farrell, K., Finnoff, J., Fraser, D., Giza, C., Greenwald, R., Hanzel, M., Hoshizaki, B., Huston, J., Jorgenson, J., Joyner, M., Krause, D., LaVoi, N., Leaf, M., Leddy, J., Leopold, J., Margarucci, K., Margulies, S., Mihalik, J., Munce, T., Ouer, A., Podein, S., Prideaux, C., Roberts, W.O., Shen, F., Soma, D., Tabrum, M., Stuart, M.B., Wethe, J., Whitehead, J., Wiese-Bjornstal, D., & Stuart, M.J. (2019). Proceedings from the Ice Hockey Summit III: Action on Concussion. Current Sport Medicine Reports, 18(1), 23-34. doi: 10.1249/JSR.0000000000000557

Fickling, S.D., Smith, A.M., Pawlowski, G., Ghosh Hajra, S., Liu, C.C., Farrell, K., Jorgensen, J., Song, X., Stuart, M.J., & D’Arcy, R.C.N. (2019). Reply: P300 amplitudes after concussion are usually decreased not increased. Brain.142(7), e33. doi: 10.1093/brain/awz147

Pawlowski, G., Ghosh Hajra, S., Fickling, S., Liu, C.C., Song, X., Robinovitch, S., Doesburg, S.M., & D’Arcy, R.C.N. (2019). Brain vital signs: Expanding from the auditory to visual modality. Frontiers in Neuroscience. 18;12:968. doi: 10.3389/fnins.2018.00968

Fickling, S.D., Smith, A.M., Pawlowski, G., Ghosh Hajra, S., Liu, C.C., Farrell, K., Jorgensen, J., Song, X., Stuart, M.J., D’Arcy, R.C.N. (2019). Brain vital signs detect concussion-related neurophysiological impairment in ice-hockey. Brain, 142(2), 255-262. Editor’s Choice. doi: 10.1093/brain/awy317

Ghosh Hajra, S., Liu, C.C., Song, X., Fickling, S.D., Cheung, T.P.L. & D’Arcy, R.C.N. (2018). Accessing knowledge of the ‘here and now’: A new technique for capturing electromagnetic markers of orientation processing. Journal of Neural Engineering, 16(1), 016008. doi: 10.1088/1741-2552/aae91e

Ghosh Hajra, S., Liu, C.C., Song, X., Fickling, S.D., Cheung, T.P., & D’Arcy, R.C.N. (2018). Multimodal characterization of the semantic N400 response within a rapid evaluation brain vital sign framework. Journal of Translational Medicine, 16(1),151. doi: 10.1186/s12967-018-1527-2

Ghosh-Hajra, S., Liu, C., Song, X., Fickling, S., Pawlowski, G. Jorgensen, J.K., Smith, A.M., Schnaider-Beeri, M., Van Den Broek, R., Rizzotti, R., Fisher, K., & D’Arcy, R.C.N. (2016). Developing Brain Vital Signs: Initial Framework for Monitoring Brain Function Changes Over Time. Frontiers of Neuroscience, Brain Imaging Methods. 10, 211. doi: 10.3389/fnins.2016.00211

Kirby, E. D., Andrushko, J. W., Rinat, S., D’Arcy, R. C. N., & Boyd, L. A. (2024). Investigating female versus male differences in white matter neuroplasticity associated with complex visuo-motor learning. Scientific reports, 14(1), 5951. https://doi.org/10.1038/s41598-024-56453-z

Frizzell, T. O., Phull, E., Khan, M., Song, X., Grajauskas, L. A., Gawryluk, J., & D’Arcy, R. (2022). Imaging functional neuroplasticity in human white matter tracts. Brain structure & function, 227(1), 381–392.

Carrick, F. R., Azzolino, S. F., Hunfalvay, M., Pagnacco, G., Oggero, E., D’Arcy, R., Abdulrahman, M., & Sugaya, K. (2021). The Pupillary Light Reflex as a Biomarker of Concussion. Life (Basel, Switzerland), 11(10), 1104.

Hill, N. J., Mooney, S., & Prusky, G. T. (2021). audiomath: A neuroscientist’s sound toolkit. Heliyon, 7(2), e06236. doi.org/10.1016/j.heliyon.2021.e06236

D’Arcy, R. C. N., Greene, T., Greene, D., Frehlick, Z., Fickling, S. D., Campbell, N., Etheridge, T., Smith, C., Bollinger, F., Danilov, Y., Livingstone, A., Tannouri, P., Martin, P., & Lakhani, B. (2020). Portable neuromodulation induces neuroplasticity to re-activate motor function recovery from brain injury: a high-density MEG case study. Journal of neuroengineering and rehabilitation, 17(1), 158. doi.org/10.1186/s12984-020-00772-5

Liu, C.C., Ghosh Hajra, S., Pawlowski, G., Fickling, S.D., Song, X., & D’Arcy, R.C.N. (2020). Differential neural processing of spontaneous blinking under visual and auditory sensory environments: An EEG investigation of blink-related oscillations, NeuroImage. 218, 116879. doi: 10.1016/j.neuroimage.2020.116879

Zhang, X., D’Arcy, R.C.N., Ming, D., & Menon, C. (2020). The Feasibility of Longitudinal Upper Extremity Motor Function Assessment Using EEG. (2019), E5487. doi: 10.3390/s20195487

Liu, C.C., Ghosh Hajra, S., Fickling, S.D., Pawlowski, G., Song, X., & D’Arcy, R.C.N. (2019). Novel signal processing technique for capture and isolation of blink-related oscillations using a low-density electrode array for bedside evaluation of consciousness. IEEE Transactions on Biomedical Engineering. Epub ahead of print. 67(2), 453-463. doi: 10.1109/TBME.2019.2915185

Frehlick, Z., Lakhani, B., Fickling, S., Livingstone, A., Danilov, Y., Sackier, J., & D’Arcy, R.C.N. (2019). Human translingual neurostimulation alters resting brain activity in high-density EEG. Journal of NeuroEngineering and Rehabilitation. 16(1), 60. doi: 10.1186/s12984-019-0538-4

Magnuson, J.R., Peatfield, N.A., Fickling, S., Nunes, A.S., Christie, G., Vakorin, V., D’Arcy, R.C.N., Ribary, U., Iarocci, G., Moreno, S., & Doesburg, S.M. (2019). Electrophysiology of inhibitory control in the context of emotion processing in children with autism spectrum disorder. Frontiers in Human Neuroscience. 12,13:78. doi: 10.3389/fnhum.2019.00078

Zhang, X., D’Arcy, R.C.N., Menon, C. (2019). Scoring upper-extremity motor function from EEG using artificial intelligence. Journal of Neural Engineering. 16 (3), 036013. doi: 10.1088/1741-2552/ab0b82

Liu, C.C., Ghosh Hajra, S., Song, X., Doesburg, S., Cheung, T.P.L., & D’Arcy, R.C.N. (2019). Cognitive loading via mental arithmetic modulates effects of blink-related oscillations on precuneus and ventral attention network regions. Human Brain Mapping, 40(2), 377-393. doi: 10.1002/hbm.24378

Fleck-Prediger, C., Ghosh Hajra, S., Liu, C.C., Gray, S., Petley, L., Weaver, D.F., Gopinath, S., Yee, E., Dick, B.D., & D’Arcy, R.C.N. (2018). Point-of-care brain injury evaluation of conscious awareness: Wide scale deployment of portable HCS EEG evaluation. Neuroscience of Consciousness. 2018(1), niy011. doi: 10.1093/nc/niy011

Liu, C.C.; Ghosh Hajra, S., Cheung, T.P., Song, X., & D’Arcy, R.C.N. (2017). Spontaneous blinks activate the precuneus: Characterizing blink-related oscillations using magnetoencephalography. Frontiers in Human Neuroscience. 11, 489. doi: 10.3389/fnhum.2017.00489

D’Arcy, R.C.N., Lindsay, D.S., Song, X., Gawryluk, J.R., Greene, D., Mayo, C., Ghosh Hajra, S., Mandziuk, L., Mathieson, J., & Greene T. (2016). Long-Term Motor Recovery After Severe Traumatic Brain Injury: Beyond Established Limits. Journal of Head Trauma Rehabilitation. 31(5), E50-8. doi: 10.1097/HTR.0000000000000185

Sculthorpe-Petley, L., Liu, C., Ghosh-Hajra, S., Boshra, R., Satel, J., Trappenberg, T.P., D’Arcy, R.C.N. (2015). A rapid event-related potential (ERP) method for point-of-care evaluation of brain function: using ERPs: Development of the Halifax Consciousness Scanner. Journal of Neuroscience Methods. 245, 64-72. doi: 10.1016/j.jneumeth.2015.02.008

Parvar, H., R., Sculthorpe-Petley, L., Satel, J., Boshra, D’Arcy, R.C.N., Trappenberg, T.P. (2015). Detection of event-related potentials in individual subjects using support vector machines. Brain Informatics. 2 (1), 1-12. doi: 10.1007/s40708-014-0006-7

D’Arcy, R.C.N., Ghosh-Hajra, S., Liu, C., Sculthorpe, L., & Weaver, D.F. (2011). Towards brain first-aid: A diagnostic device for conscious awareness. IEEE Transactions on Biomedical Engineering. 58(3), 750-4. doi: 10.1109/TBME.2010.2090880. Early access IEEE Xplore.

Versteeg, V., Marchand, Y., Mazerolle, E.L., & D’Arcy, R.C.N. (2010). Profiling brain function: Spatiotemporal characterization of normal and abnormal visual evoked potential. Journal of Neuroscience Methods. 190(1), 95-105. doi: 10.1016/j.jneumeth.2010.04.015

Gawryluk, J.R., D’Arcy, R.C.N., Connolly, J.F., & Weaver, D.F. (2010). Improving the clinical assessment of consciousness with advances in electrophysiology and neuroimaging techniques. BMC Neurology. 10:11. doi: 10.1186/1471-2377-10-11

Gawryluk, J.R. & D’Arcy, R.C.N. (2010). Electroencephalography: Basic concepts and brain applications. Handbook of Physics in Medicine and Biology. R. Splinter (Ed.). Taylor and Francis.

Mazerolle, E.L., D’Arcy, R.C.N., Marchand, Y.M., & Bolster, R.B. (2007). ERP assessment of functional status of the temporal lobe: Examining spatiotemporal correlates of object recognition. International Journal of Psychophysiology. 66(1), 81-92. doi: 10.1016/j.ijpsycho.2007.06.003

Connolly, J.F., Marchand, Y., Major, A., & D’Arcy, R.C.N. (2006). Event-related brain potentials as a measure of performance on WISC-III and WAIS-R NI Similarities sub-tests. Journal of Clinical and Experimental Neuropsychology. 28(8), 1327-1345. doi: 10.1080/13803390500428484

D’Arcy, R.C.N., Service, E., Connolly, J.F., & Hawco, C.S. (2005). The influences of increased working memory load on semantic neural systems: A high-resolution event-related brain potential study. Cognitive Brain Research. 22 (2), 177-191. doi: 10.1016/j.cogbrainres.2004.08.007

D’Arcy, R.C.N., Connolly, J.F., Service, E., Hawco, C.S., & Houlihan, M.E. (2004). Separating phonological and semantic processing in auditory sentence processing: A high-resolution event-related brain potential study. Human Brain Mapping. 22 (1), 40-51. doi: 10.1002/hbm.20008

D’Arcy, R.C.N., Marchand, Y., Eskes, G.A., Harrison, E.R, Major, A., Phillips, S.J., & Connolly, J.F. (2003). Electrophysiological assessment of language function following stroke. Clinical Neurophysiology. 114 (4), 662-672. doi: 10.1016/s1388-2457(03)00007-5

Marchand, Y., D’Arcy, R.C.N., & Connolly, J.F. (2002). Linking neurophysiological and neuropsychological measures for aphasia assessment. Clinical Neurophysiology. 113(11), 1715-22. doi: 10.1016/s1388-2457(02)00224-9

Connolly, J.F., Service, E., D’Arcy, R.C.N., Kujala, A., & Alho, A. (2001). Phonological aspects of word recognition as revealed by high-resolution spatio-temporal brain mapping. NeuroReport, 12(2), 237-43. doi: 10.1097/00001756-200102120-00012

D’Arcy, R.C.N., Connolly, J.F., & Eskes, G.A. (2000). Evaluation of reading comprehension with neuropsychological and event-related brain potential (ERP) methods. Journal of the International Neuropsychological Society. 6(5), 556-67. doi: 10.1017/s1355617700655054

D’Arcy, R.C.N., Connolly, J.F., & Crocker, S.F. (2000). Latency shifts in the N2b component track phonological deviations in spoken words. Clinical Neurophysiology. 111(1), 40-4. doi: 10.1016/s1388-2457(99)00210-2

Connolly, J.F., D’Arcy, R.C.N., Newman R.L. & Kemps, R. (2000). The application of cognitive event-related brain potentials in language-impaired individuals: Review and case studies. Invited review. International Journal of Psychophysiology. 38(1), 55-70. doi: 10.1016/s0167-8760(00)00130-6

Connolly, J.F., & D’Arcy, R.C.N. (2000). Innovations in neuropsychological assessment using event-related brain potentials. Invited review. International Journal of Psychophysiology. 37(1), 31-47. doi: 10.1016/s0167-8760(00)00093-3

Mateer C.A., & D’Arcy, R.C.N. (2000). Current concepts in assessment and management. S. Raskin & C. Mateer (Eds.). Neuropsychological Management of Mild Traumatic Brain Injury. New York: Oxford University Press.

D’Arcy, R.C.N., & Connolly, J.F. (1999). An event-related brain potential study of receptive speech comprehension using a modified Token Test. Neuropsychologia. 37(13), 1477-1489. doi: 10.1016/s0028-3932(99)00057-3

Connolly, J.F., Major, A.M., Allen, S.L., & D’Arcy, R.C.N. (1999). Performance on WISC-III and WAIS-R NI vocabulary subtests assessed with event-related brain potentials: An innovative method of assessment. Journal of Clinical and Experimental Neuropsychology. 21(4), 444-464. doi: 10.1076/jcen.21.4.444.879.

Email: [email protected]
Phone: 1-844-847-1264
NeuroCatch Inc.
Unit 1009, City Centre 3
13761 96 Avenue, Surrey, BC V3V 0E8
Canada

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The NeuroCatch® Platform is intended to be used in conjunction with other cognitive assessments and is not a diagnostic tool for a specific brain health condition. It is not to be used as a standalone diagnostic device.